๐ฑ
Introduction — What is a Cell?
Scientists believe life originated in water — possibly in
small pools with changing environmental conditions, like the hot
springs of Puga Valley, Ladakh. These maintain temperatures near the
boiling point even in cold climates, similar to early Earth about 3.5 billion
years ago.
๐️
๐ฌ Cell — The Basic Unit
of Life
A cell (เคोเคถिเคा) is
the basic structural and functional unit of all living organisms. Every living
thing — from a tiny bacterium to a giant blue whale — is made of cells.
๐ Organization of Life
Cell → Tissue → Organ → Organ System → Organism
Example: Nasal pores + Nasal cavity + Trachea + Lungs
= Respiratory System
๐
๐ญ
How to Study Cells — Microscopy
Cells are too small to be seen by the unaided eye. So
scientists use microscopes (เคธूเค्เคท्เคฎเคฆเคฐ्เคถी) to
study them.
๐️ Limit of Resolution of
Human Eye
Limit of Resolution of Human Eye = 0.1 mm
When two points are closer than 0.1 mm (viewed from 25 cm),
we cannot see them as separate — they appear as one point.
๐️ Robert Hooke — First
Cell Observer
๐ฌ
๐ฌ Types of Microscopes
๐ Activity: Estimating
Cell Size
Estimated Cell Size = (Diameter of visible field in
ยตm) ÷ (Number of cells along the diameter)
Example Calculation:
Size of one cell = 5000 ÷ 25 = 200 ยตm
๐ก
๐ Three Features of a
Good Microscope
- Resolution —
measure of clarity (how clearly two close points appear separate)
- Contrast —
difference in brightness between various parts of an object
- Magnification —
how many times the image appears larger than the object
๐งฉ
Structure of a Cell — Membrane, Wall & Interior
๐ก️ Cell Membrane (Plasma
Membrane)
The cell membrane (เคोเคถिเคा เคिเคฒ्เคฒी) is
a thin boundary surrounding every cell, protecting its contents. It is also
called the plasma membrane.
๐
๐ Fluid-Mosaic Model
- Lipid
bilayer: Two layers of fat molecules — hydrophilic heads facing
outward, hydrophobic tails facing inward
- Fluid:
Molecules can move sideways, flip and rotate within the membrane
- Mosaic:
Proteins are embedded in the lipid bilayer, arranged like tiles in a
mosaic
- Proteins
act as gatekeepers — helping substances pass through
๐ง Osmosis (เคชเคฐाเคธเคฐเคฃ) — Water Movement
๐
|
Solution Type |
Condition |
Effect on Cell |
|
Isotonic |
Extracellular conc. = Intracellular conc. |
No change in cell size ⚖️ |
|
Hypotonic |
Extracellular conc. < Intracellular conc. |
Cell swells (water enters) ๐บ |
|
Hypertonic |
Extracellular conc. > Intracellular conc. |
Cell shrinks (water exits) ๐ป |
๐ฅ Potato Experiment
(Activity 2.2):
Beaker A (Plain Water) → Hypotonic → Potato
piece SWELLS (water enters by osmosis)
Beaker B (20% Salt Solution) → Hypertonic →
Potato piece SHRINKS (water exits by osmosis)
โน️
๐งฑ Cell Wall (เคोเคถिเคा เคญिเคค्เคคि)
Present in plant cells, fungi, and bacteria. It
is an additional rigid layer outside the cell membrane. It is NOT
present in animal cells.
๐ก
⚙️
Cell Organelles — The Tiny Workers Inside
A cell is like a tiny factory — each
organelle (เค
ंเคเค) has a
specific job. The cytoplasm contains many membrane-bound organelles, most
visible only with an electron microscope.
๐ฌ Prokaryotic vs
Eukaryotic Cells
|
Feature |
Prokaryotic Cell |
Eukaryotic Cell |
|
Nucleus |
Absent (has nucleoid) |
Well-defined, membrane-bound |
|
Cell diameter |
1–10 ยตm |
10–100 ยตm |
|
Membrane-bound organelles |
Absent |
Present |
|
Examples |
Bacteria |
Plant, Animal, Fungal cells |
|
Number of cells |
Usually unicellular |
Can be unicellular or multicellular |
๐️ All Key Organelles at
a Glance
๐ง
Nucleus
“Control Centre”
Controls all cell activities. Contains DNA (genes).
Double-layered nuclear membrane with pores.
๐ญ
Ribosomes
“Protein Factories”
Site of protein synthesis. Found freely in cytoplasm or
attached to RER. No membrane around them.
๐ธ️
Endoplasmic Reticulum (ER)
“Manufacturing & Transport”
Network in cytoplasm. RER: protein synthesis. SER: lipid
& hormone synthesis.
๐ฆ
Golgi Apparatus
“Post Office of Cell”
Modifies, sorts & packages proteins/lipids. Sends them
to right destination. Forms lysosomes.
๐งน
Lysosomes
“Suicide Bags / Cleaners”
Single membrane sacs with digestive enzymes. Break down
waste, damaged organelles, and foreign particles.
⚡
Mitochondria
“Powerhouse of the Cell”
Site of cellular respiration. Produces ATP (energy). Has its
own DNA and ribosomes!
๐ฟ
Chloroplast
“Kitchen of the Cell”
Contains chlorophyll. Site of photosynthesis. Found only in
plant cells. Has own DNA!
๐ง
Vacuoles
“Storage Tank”
Stores water, minerals, sugars, waste. Large central vacuole
in plant cells. Maintains cell turgor.
๐ง Nucleus — In Detail
- Nuclear
membrane: Double-layered covering with nuclear pores (allow material
transfer)
- Nucleolus:
Dense body inside nucleus where ribosomal subunits are made
- Chromosomes:
Rod-shaped structures visible only during cell division; made of DNA
+ proteins
- Genes:
Functional segments of DNA that carry genetic information
- Chromatin:
Loosely coiled DNA in non-dividing cells (looks like tangled threads)
DNA → Chromatin (non-dividing) ↔ Chromosomes
(dividing)
โน️
๐ธ️ Endoplasmic Reticulum
— Two Types
๐ฌ
⚡ Mitochondria — Powerhouse
- Double
membrane bound organelle
- Inner
membrane has finger-like folds called cristae — increase
surface area for reactions
- Site
of cellular respiration — glucose broken down to release
energy
- Energy
stored as ATP (Adenosine Triphosphate) — the energy
currency of the cell
- Has
its own DNA and ribosomes — can make some proteins
independently
๐ฟ Plastids — Only in
Plant Cells
|
Plastid Type |
Contains |
Function / Location |
|
Chloroplast |
Chlorophyll (green pigment) |
Photosynthesis — green leaves |
|
Chromoplast |
Yellow, orange, red pigments |
Colour in flowers and fruits; attracts pollinators |
|
Leucoplast |
No pigment (colourless) |
Stores starch, oils, proteins — potato stores starch |
๐ธ
๐ง Vacuoles
๐ฟ
Plant Cell vs Animal Cell vs Bacterial Cell
One of the most important comparison tables for exams! Know
what is present and absent in each type of cell.
๐ฟ Plant Cell
- Cell
membrane ✓
- Cell
wall (Cellulose) ✓
- Nucleus
(defined) ✓
- Mitochondria
✓
- Chloroplasts
✓
- Large
central vacuole ✓
- ER,
Golgi, Ribosomes ✓
- Lysosomes
(rare) ✗
- Centrioles
✗
๐พ Animal Cell
- Cell
membrane ✓
- Cell
wall ✗
- Nucleus
(defined) ✓
- Mitochondria
✓
- Chloroplasts
✗
- Large
vacuole ✗
- ER,
Golgi, Ribosomes ✓
- Lysosomes
✓
- Centrioles
✓
๐ฆ Bacterial Cell
- Cell
membrane ✓
- Cell
wall ✓
- Defined
nucleus ✗
- Nucleoid
(DNA) ✓
- Mitochondria
✗
- Chloroplasts
✗
- Ribosomes
(70S) ✓
- Membrane
organelles ✗
⚠️
๐ก
๐
Cell Division — Mitosis & Meiosis
When you get a cut on your skin, it heals. When hair falls
out, new hair grows. Why? Because cells grow and divide to
replace old, dead, or damaged cells. Every day, hundreds of billions of cells
in your body are replaced (about 1% of total cells)!
๐ Cell Division —
Overview
Cell division (เคोเคถिเคा
เคตिเคญाเคเคจ) is
the process by which new cells are formed from pre-existing cells. There are
two major types:
๐ต Mitosis (เคธूเคค्เคฐी เคตिเคญाเคเคจ)
๐ฃ Meiosis (เค
เคฐ्เคงเคธूเคค्เคฐी เคตिเคญाเคเคจ)
๐ต Mitosis — The Common
Division
- Every
human starts life as a single fertilised egg (zygote)
- This
one cell divides by mitosis into trillions of body cells
- Produces
two genetically identical daughter cells
- Each
new cell gets the same DNA and same number of chromosomes as
the parent
- Controlled
by the cell cycle — errors can cause tumours!
๐ฃ Meiosis — The Special
Division
- First
Division: Cell divides into 2 daughter cells; chromosome number
is halved (2n → n)
- Second
Division: Each daughter cell divides again (like mitosis); result
= 4 daughter cells with half chromosomes
- During
fertilisation, two gametes combine to restore the original chromosome
number
|
In Animals |
Meiosis Occurs In |
|
Males |
Testes → produces sperm cells |
|
Females |
Ovaries → produces egg cells |
โน️
⚠️
๐งฌ
๐
Cell Theory — The Unifying Principle of Biology
Cell Theory unifies all of biology — from bacteria to
humans. It explains life’s continuity through cell division.
๐
History of Cell Theory
|
Year |
Scientist |
Contribution |
|
1665 |
Robert Hooke |
First observed cells in cork; named them “cells” |
|
1838 |
Matthias Schleiden (German Botanist) |
All plants are made of cells |
|
1839 |
Theodor Schwann (German Zoologist) |
All animals are made of cells |
|
1855 |
Rudolf Virchow (German Scientist) |
New cells arise only from pre-existing cells |
๐ The Three Points of
Classical Cell Theory
- All
living organisms are made up of one or more cells.
- The
cell is the basic unit of structure and function in living beings.
- All
cells arise from pre-existing cells.
๐ฌ
๐ Do Cells Live Forever?
- Every
cell has a definite lifespan — cells grow, function, and
eventually die
- Dead
cells are replaced by new cells through division
- Programmed
Cell Death (PCD): Genetically regulated cell death — essential for
normal development (e.g., forming fingers by eliminating cells between
digits)
- Cancer:
Cells lose control and divide uncontrollably → benign or malignant tumours
✍
Quick Revision Summary
One-liner review of all key concepts
๐ฌ CellBasic
structural and functional unit of all living organisms (เคोเคถिเคा)
๐ก️ Cell MembraneSelectively
permeable; made of lipids + proteins; controls what enters/exits
๐งฑ Cell WallIn plants,
fungi, bacteria; mainly cellulose in plants; provides rigidity; permeable
๐ง OsmosisWater moves
from dilute → concentrated solution through selectively permeable membrane
๐ฆ ProkaryoticNo
defined nucleus, no membrane organelles; 1–10 ยตm; e.g., Bacteria
๐ฟ EukaryoticDefined
nucleus + membrane organelles; 10–100 ยตm; plants, animals, fungi
๐ง Nucleus“Control
Centre” — contains DNA in chromosomes; double nuclear membrane
⚡ Mitochondria“Powerhouse” —
produces ATP via cellular respiration; has own DNA
๐ฟ Chloroplast“Kitchen”
— photosynthesis; contains chlorophyll; only in plant cells; has own DNA
๐ฆ Golgi Apparatus“Post
Office” — modifies, sorts, packages proteins for secretion or lysosomes
๐งน Lysosomes“Suicide
Bags” — contain digestive enzymes; clean up waste and damaged parts
๐ต Mitosis2 identical
daughter cells; same chromosomes; for growth and repair
๐ฃ Meiosis4 gametes;
half chromosomes; for sexual reproduction; 2-step process
๐ Cell TheorySchleiden
+ Schwann + Virchow; all organisms are made of cells; cells from cells
๐ Fluid-Mosaic ModelLipid
bilayer with embedded proteins; fluid (moves) + mosaic (tiled pattern)
⚠️ CancerUncontrolled cell
division due to loss of contact inhibition → tumours
๐
Important Exam Questions
Practice these for CBSE board preparation
Q1. What is osmosis? How does the osmosis experiment with
potato pieces demonstrate the selectively permeable nature of the cell
membrane? (CBSE-type / 3 Marks)
Ans: Osmosis is the movement of water
through a selectively permeable membrane from a region of higher water
concentration (dilute solution) to a region of lower water concentration
(concentrated solution). In the potato experiment: Potato in plain water
(hypotonic) → swells (water enters by osmosis). Potato in 20% salt solution
(hypertonic) → shrinks (water exits by osmosis). This shows that the cell
membrane allows water molecules to pass but NOT salt/sugar molecules, proving
it is selectively permeable.
Q2. Differentiate between Mitosis and Meiosis. (CBSE-type
/ 3 Marks)
Ans: Mitosis: Produces 2 daughter cells;
daughter cells are genetically identical to parent; chromosome number remains
same (2n→2n); occurs in somatic (body) cells; purpose is growth and
repair. Meiosis: Produces 4 daughter cells (gametes); daughter
cells are genetically diverse; chromosome number is halved (2n→n); occurs only
in reproductive organs (testes, ovaries); purpose is sexual reproduction.
Q3. Why is the cell membrane called selectively
permeable? How is the fluid-mosaic model explained? (CBSE-type / 3 Marks)
Ans: The cell membrane is called selectively
permeable because it allows some substances to pass through it while
blocking others (e.g., allows water but not salt molecules). The Fluid-Mosaic
Model explains that: (1) The membrane has a lipid bilayer with
hydrophilic heads outward and hydrophobic tails inward; (2) Proteins are
embedded in this layer — it is called ‘mosaic’ as proteins are arranged like
tiles; (3) Molecules can move sideways/rotate — so it is called ‘fluid.’
Q4. Compare the structure of a prokaryotic cell and a
eukaryotic cell. Give one example of each. (CBSE-type / 3 Marks)
Ans: Prokaryotic Cell: No defined nucleus
(has nucleoid instead), no membrane-bound organelles, diameter 1–10 ยตm, usually
unicellular. Example: Bacteria. Eukaryotic Cell: Well-defined
nucleus with nuclear membrane, has membrane-bound organelles (mitochondria, ER,
Golgi, etc.), diameter 10–100 ยตm, can be unicellular or multicellular. Example:
Plant cells, animal cells.
Q5. Why are mitochondria called the “powerhouses of the
cell”? What is ATP? (CBSE-type / 2 Marks)
Ans: Mitochondria are called the powerhouses of the cell
because they supply energy to almost all cellular activities. In mitochondria,
glucose is broken down during cellular respiration to release
energy. This energy is stored in a molecule called ATP (Adenosine
Triphosphate), which acts as the energy currency of the cell and is used
for most cellular activities like movement, synthesis, and active transport.
Q6. What is the Cell Theory? Name the three scientists
who contributed to it. (CBSE-type / 3 Marks)
Ans: Cell Theory states: (1) All living
organisms are made up of one or more cells. (2) The cell is the basic unit of
structure and function. (3) All cells arise from pre-existing cells.
Contributors: Matthias Schleiden (1838) — all plants made of
cells; Theodor Schwann (1839) — all animals made of
cells; Rudolf Virchow (1855) — new cells form only from
pre-existing cells.
๐ฏ
๐